The TIMES study seeks to gain a better understanding of how insulin sensitivity changes over the course of the menstrual cycle in women with type 1 diabetes (T1D). This study aims to enable improved technology such as automated insulin delivery (AID) systems that can automatically adapt to hormonal fluctuations associated with the menstrual cycle. More details here: https://www.dcberne.com/en/times-study/.

Background: Premenopausal women with type 1 diabetes (T1D) often experience changes in blood sugar control related to their menstrual cycle. These natural hormone fluctuations can make diabetes management difficult, especially since current AID systems are not designed to adjust insulin delivery in response to these monthly hormonal changes.

The TIMES study was developed to gain robust scientific insights into how insulin requirements and blood glucose control change during the menstrual cycle. The multinational study is being conducted in a decentralized manner and includes a total of 350 women, approximately 50 each in Switzerland, Denmark, the UK, the US, and Germany. As this is a decentralized study, all study-related activities take place online or at the participants’ homes. It is not necessary to visit a clinic or medical center.

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